ZHONG Han1; GAN Lixia1; ZHANG Weimin1; PAN Qingling1; LI Haohua1; TAO Meihua1; WANG Lei1; TAN Yuzhi2; LIU Yanping31Guangdong Institute of Microbiology; Guangzhou; Guangdong 510070; China; 2Guangdong College of Pharmacy; Guangzhou; Guangdong 510006; China; 3Guangdong Jin Chongcao Biological Development Co.Ltd.; Guangzhou; Guangdong 510620; China
【中文摘要】 The polysaccharide,adenosine and mannitol components of Cordyceps taii collected from the wild were determined,and the effects of aqueous C.taii extracts on immune functions in mice were investigated using carbon clearance and delayed-type hypersensitivity testing(DTH),and by determining thymic and splenic indices.Polysaccharide,adenosine and mannitol levels in C.taii were 36.20 mg/g,0.27 mg/g and 80.20 mg/g,respectively.Aqueous C.taii extracts partially alleviated the suppressive effects on the...更多 thymic and splenic indices caused by cyclophosphamide,and increased nonspecific immunity and cellular immune functions.Toxicity tests revealed that the LD50 for aqueous C.taii extract on oral administration was >69.42 g/kg. 还原
【英文摘要】 The polysaccharide,adenosine and mannitol components of Cordyceps taii collected from the wild were determined,and the effects of aqueous C.taii extracts on immune functions in mice were investigated using carbon clearance and delayed-type hypersensitivity testing(DTH),and by determining thymic and splenic indices.Polysaccharide,adenosine and mannitol levels in C.taii were 36.20 mg/g,0.27 mg/g and 80.20 mg/g,respectively.Aqueous C.taii extracts partially alleviated the suppressive effects on the thymic and splenic indices caused by cyclophosphamide,and increased nonspecific immunity and cellular immune functions.Toxicity tests revealed that the LD50 for aqueous C.taii extract on oral administration was >69.42 g/kg.
【英文关键词】 Cordyceps taii; polysaccharide; adenosine; mannitol; carbon clearance; cellular immune function
【基金】the Foundation of Guangdong Province(No.2005B33701016 and No.2006B20201038)
【文献出处】 食用菌学报,Acta Edulis Fungi,编辑部邮箱,2008年03期 【DOI】CNKI:SUN:SYJB.0.2008-03-014