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Flavone Content and Bioactivity of Aqueous-Ethanolic Extracts of Phellinus Fruit Bodies

2010-05-17 10:521790

HAO Ruixia1; ZHOU Shuai1; YANG Yan1; XI Junzhe2; LI Weiyao2; TANG Qingjiu1; WANG Chenguang11 Shanghai Biotechnology and Engineering Research Center for the Edible Fungi; Key Laboratory of Agricultural Genetics and Breeding of Shanghai; Research Center of Natural Medicinal Resources; Institute of Edible Fungi; Shanghai Academy of Agricultural Sciences; Shanghai 201106; China; 2 College of Food Science and Technology; Shanghai Fisheries University; Shanghai 200090; Chin

【中文摘要】 The flavone content of aqueous ethanolic extracts of Phellinus fruit bodies obtained from seven different locations was determined.Anti-tumor and antioxidant activities associated with the extracts were investigated in vitro using the Alamar Blue assay and a chemiluminecence-based method,respectively.Extracts of the seven Phellinus samples generated very similar HPLC profiles in qualitative terms although the areas of several peaks varied according to the sample type indicating quantitative diff...更多erences in the case of some components.All the extracts,especially those of artificially cultivated Phellinus baumii fruit bodies,inhibited L1210 tumor cell proliferation and exhibited superoxide radical scavenging activity although there was no obvious correlation with flavone content.  还原

【英文摘要】 The flavone content of aqueous ethanolic extracts of Phellinus fruit bodies obtained from seven different locations was determined.Anti-tumor and antioxidant activities associated with the extracts were investigated in vitro using the Alamar Blue assay and a chemiluminecence-based method,respectively.Extracts of the seven Phellinus samples generated very similar HPLC profiles in qualitative terms although the areas of several peaks varied according to the sample type indicating quantitative differences in the case of some components.All the extracts,especially those of artificially cultivated Phellinus baumii fruit bodies,inhibited L1210 tumor cell proliferation and exhibited superoxide radical scavenging activity although there was no obvious correlation with flavone content.

【英文关键词】 Phellinus; flavones; antitumor; antioxidation
【基金】the Shanghai Science and Technolgy Office(Grant No.063919143)

【文献出处】 食用菌学报,Acta Edulis Fungi,编辑部邮箱,2008年02期 【DOI】CNKI:SUN:SYJB.0.2008-02-008

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