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Anti-Tumor Function of Polysaccharides from Pholiota adiposa Mycelium

2010-05-17 09:490

ZHAO Yongxun; LI Keying; ZHANG YuehuaCollege of Life Sciences; Jiamusi University; Jiamusi; Heilongjiang 154007; China

【中文摘要】 Treatment of S-180 tumor-bearing mice with polysaccharide extracted from Pholiota adiposa mycelium resulted in lower tumor weights, increased carbon particle clearance and phagocytic indices, and significantly higher serum levels of TNF-α and IL-2, compared with untreated controls. Our data suggest that the anti-tumor activity of P. adiposa polysaccharide is related to immuno-enhancing activity.

【英文摘要】 Treatment of S-180 tumor-bearing mice with polysaccharide extracted from Pholiota adiposa mycelium resulted in lower tumor weights, increased carbon particle clearance and phagocytic indices, and significantly higher serum levels of TNF-α and IL-2, compared with untreated controls. Our data suggest that the anti-tumor activity of P. adiposa polysaccharide is related to immuno-enhancing activity.

【英文关键词】 Carbon particle clearance index; Interleukin-2; Pholiota adiposa; Polysaccharide; Tumor necrosis factor-alpha

【文献出处】 食用菌学报,Acta Edulis Fungi,编辑部邮箱,2007年02期 【DOI】CNKI:SUN:SYJB.0.2007-02-012

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